Lora Mutisheva was born on March 13, 1981 in Sofia. She graduated from French language school “Saint Sofia” in 1999. She graduated from The National Academy for Theatre and Film Arts in 2005 with a degree in Acting in the class of professor Plamen Markov. Before that, she participated for one year in the class of professor Nikola Korabov “Acting for cinema and television” at MDFI. Since 2002 she is on the professional scene in the plays “Maesters” (New Dramatic Theatre “Tear and Laughter”), “Macbeth” from Plamen Markov (National Theatre “Ivan Vazov”), together with the roles of Desdemona in “Othello”, Sasha in “Platonov” (director Alexander Sabev), The Nurse in “Romeo and Juliet” (directors Ivaylo Hriston and Atanas Atanasov), and others. In 2003 she took part in the European Youth Music Festival in Passau, Germany with Vocal chamber ensemble "Theatre collegium ", conductor Prof . Dr. Rumen Tsonev.
In 2006 and 2007 she took part in concerts, dedicated to the “Night of Museums and Galleries” in Stara Zagora and Plovdiv, together with a joint concert with Big Band “Stara Zagora”. In 2005 she joined the ensembre of the Stara Zagora Theatre, where she played over ten roles, among which Stefka in “The Elevator” (director Kalin Angelov), Sarah in “Mister Colpert” (director Garo Ashikyan), Miss Frateva in ”Rage” (director Plamen Markov), Teibele in “Teibele and her demon” (director Plamen Markov), and others. In the period 2005-2008 she is the host of the BNT`s TV show “My language”. At the current moment, she is an assistant lecturer at the “Stage Speech” department at The National Academy for Theatre and Film Arts. Since 2010 she is a part of the ensemble of Sofia Theatre.